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Allergic reactions to penicillin are an example of a


A) Type 1 hypersensitivity.
B) Type 2 hypersensitivity.
C) Type 3 hypersensitivity.
D) Type 4 hypersensitivity.

E) A) and B)
F) A) and C)

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At birth, a neonate with blood Type O will have circulating anti-A and anti-B antibodies.

A) True
B) False

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One theory regarding immune tolerance and the development of autoimmunity states that during embryonic growth, some tissues are hidden behind anatomical barriers and cannot be surveyed by the developing immune system.Later in life, some of these tissues may be exposed to the immune system as a result of trauma or infection and the immune system responds by developing an immune reaction against these tissues as if they were foreign.This theory is the


A) theory of molecular mimmicry.
B) theory of immune deficiency.
C) forbidden clone theory.
D) sequestered antigen theory.

E) A) and D)
F) B) and C)

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All of the following are involved in Type 2 hypersensitivity, except


A) IgM.
B) IgG.
C) IgE.
D) complement.
E) foreign cells.

F) A) and D)
G) B) and C)

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Any heightened or inappropriate immune response resulting in tissue damage is called a/an


A) autoimmune disease.
B) immunodeficiency.
C) hypersensitivity.
D) transfusion reaction.
E) desensitization.

F) A) and C)
G) C) and D)

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Epinephrine


A) is an antihistamine.
B) reverses constriction of airways.
C) causes desensitization.
D) inhibits the activity of lymphocytes.
E) All of these choices are correct.

F) A) and C)
G) A) and B)

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The potential for hemolytic disease of the newborn occurs when


A) maternal Rh+ cells enter an Rh− fetus.
B) fetal Rh+ cells enter an Rh− mother.
C) maternal Rh− cells enter an Rh+ fetus.
D) fetal Rh− cells enter an Rh+ mother.
E) fetal Rh+ cells enter an Rh+ mother.

F) A) and D)
G) All of the above

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Histamine causes all the following, except


A) increased sensitivity to light.
B) constriction of smooth muscle of bronchi and the intestine.
C) relaxes vascular smooth muscle.
D) wheal and flare reaction in skin.
E) pruritis and headache.

F) A) and E)
G) None of the above

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Which of the following is a risk of a bone marrow transplant that is not typically a risk of a kidney or heart transplant?


A) host rejection of graft
B) graft versus host disease
C) formation of autoantibodies
D) hypogammaglobulinemia

E) A) and B)
F) C) and D)

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During graft rejection, cytotoxic T-cells of the recipient recognize and respond to foreign Class I MHC receptors on the grafted cells.

A) True
B) False

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All of the following are involved in the development of a Type 4 hypersensitivity reaction, except


A) antigen.
B) TH cells.
C) IgE.
D) cytokines.
E) TC cells.
F) dendritic cells.
G) macrophages.

H) A) and E)
I) C) and G)

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The chemical mediator that causes prolonged bronchospasm, vascular permeability, and mucus secretion of asthmatic patients is


A) prostaglandin.
B) histamine.
C) leukotriene.
D) serotonin.
E) platelet-activating factor.

F) C) and D)
G) All of the above

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Which of the items below accurately describe characteristics of Type 4 hypersensitivity reactions.Check all that apply.


A) Reactions occur within minutes of antigen exposure (provocative dose) .
B) Reactions are generated by components of the cell-mediated immune response.
C) IgE, basophils, and mast cells are typically involved.
D) Histamine is a major mediator of symptoms.
E) Reactions are delayed for 24- 48 hours after provocative antigen exposure.
F) The tuberculin skin test and the rash caused by poison ivy and poison oak are examples.

G) B) and C)
H) A) and C)

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Tissue transplanted from one body site on a patient to a different body site on that patient is called an _____.

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The antigens to which allergic individuals are sensitive are termed _____.

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A female who is Rh+


A) inherited two recessive genes.
B) is in the majority of the population with regard to Rh status.
C) is at risk for a pregnancy resulting in hemolytic disease of the newborn.
D) can only have an Rh positive baby.
E) All of these choices are correct.

F) B) and E)
G) None of the above

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Which of the following can be a consequence of a genetic deficiency in B cell survival and maturity?


A) host rejection of graft
B) graft versus host disease
C) formation of autoantibodies
D) hypogammaglobulinemia

E) B) and C)
F) A) and B)

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